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Bempedoic acid shows promise for LDL lowering in high-risk patients  Healio

NEW ORLEANS — Treatment with bempedoic acid, an investigational oral, once-daily therapy that is designed to work in the liver to inhibit cholesterol ...

Does Age Affect Alirocumab Efficacy in Heterozygous Familial Hypercholesterolemia?  The Cardiology Advisor

Alirocumab was found to be both safe and effective in reducing LDL-C in patients with heterozygous familial hypercholesterolemia.

Alzheimer's and Longevity Genes: Are They Connected?  MedPage Today

A life-extending gene variant may protect people at risk for AD.

'Gentler cure' technique produces delay in viral rebound in some people taken off HIV therapy  aidsmap

Researchers have introduced genetic changes into human T-cells that make them virtually immune to HIV infection, and the viral load in HIV-positive people ...

GD Biomarker Chitotriosidase Not Associated with Symptom Severity in Untreated Patients, Study Reports  Gaucher Disease News

Read about a study reporting that the plasma activity of chitotriosidase is not associated with clinical severity of Gaucher disease in untreated patients.

CRISPR-mediated gene activation rescues obesity caused by haploinsufficiency [PreClinical]  2 Minute Medicine

1. Haploinsufficiency of Sim1 or Mc4r in the hypothalamus result in an obesity phenotype in mice and humans. 2. In mice, CRISPR-mediated activation ...

Top stories in cardiology: FDA approves new generic valsartan, smartwatch detects atrial fibrillation  Healio

Among the top cardiology stories last week were the FDA approval of a generic form of valsartan to address recalls of that same type of drug and results of an ...

Heterozygous mutations cause genetic instability in a yeast model of cancer evolution  Nature.com

Genetic instability, a heritable increase in the rate of genetic mutation, accelerates evolutionary adaptation and is widespread in cancer. In mammals, instability ...

HSD3B1 Variants Linked With Outcomes of Prostate Cancer Treatments  Cancer Network

HSD3B1 genotype may be a predictive biomarker for the use of androgen deprivation therapy (ADT) or abiraterone in Japanese men with prostate cancer, ...

A New Idea about How Cancer Begins  Scientific American

Cells, the units of life that compose our bodies, are able to make copies of themselves to help us grow, fight disease and recover from injuries. Cells have built-in ...

LilBub, Sequenced  GenomeWeb

A famous Internet cat has had its genome sequenced to home in on two variants that may account for its appearance.

Does Candida grow on trees?  Newswise

Newswise — At one point or another, most people have played host to the common yeast Candida albicans. Around 40-60% of healthy adults carry around it in ...

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Studies of Crossing-over in Heterozygous Translocation in Drosophila melanogaste
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To Determine Genetical Ratios when Selfing Organisms Heterozygous for Two or Mor
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Zygosity - Wikipedia
Types. The words homozygous, heterozygous, and hemizygous are used to describe the genotype of a diploid organism at a single locus on the DNA. Homozygous describes a genotype consisting of two identical alleles at a given locus, heterozygous describes a genotype consisting of two different alleles at a locus, hemizygous describes a genotype consisting of only a single copy of a particular ...

Heterozygous | Define Heterozygous at Dictionary.com
Although the mother was fertilized by a normal male, every daughter is heterozygous for one or the other of the lethal factors.

Heterozygous | Definition of Heterozygous by Merriam-Webster
Recent Examples on the Web. Using a dataset of the genomes of more than 400 deceased people, the researchers looked for instances of heterozygous genes: genes that are the result of a person inheriting a human gene from one parent and a Neanderthal gene from another. — Ben Panko, Smithsonian, "How Ancient Neanderthal DNA Still Influences Our Genes Today," 24 Feb. 2017 Using a dataset of the ...

Heterozygote | biology | Britannica.com
In human genetic disease: Autosomal dominant inheritance. It manifests itself in the heterozygote (designated Aa), who receives a mutant gene (designated a) from one parent and a normal (“wild-type”) gene (designated A) from the other.In such a case the pedigree (i.e., a pictorial representation of family history) is vertical—that is, the disease passes from one generation…

Tobiano - Wikipedia
Tobiano is a spotted color pattern commonly seen in Pinto horses, produced by a dominant gene.The tobiano gene produces white-haired, pink-skinned patches on a base coat color. The coloration is almost always present from birth and does not change throughout the horse's lifetime, unless the horse also carries the gray gene. (see below) It is a dominant gene, so any tobiano horse must have at ...

Biology Dictionary - H - Macroevolution.net
Biology Dictionary - H to HYSTRIX: Meanings of biology terminology and abbreviations starting with the letter H.

Basic Principles of Genetics: Glossary of Terms
the genetically inherited condition in which there is a marked deficiency of pigmentation in skin, hair, and eyes. An individual with these traits is an "albino."

Heterozygous Factor V Leiden - Medical Auditing - AAPC
I'm looking for opinions/suggestions regarding the most appropriate ICD 10 code for a patient who is heterozygous for the Factor V Leiden mutation. I'

Mutation Detection with CodonCode Aligner: Find SNPs ...
Mutation Detection. CodonCode Aligner offers several features and methods for the detection and analysis of heterozygous point mutations: Calling secondary peaks in sequence traces

List of High Cholesterol, Familial Heterozygous ...
About High Cholesterol, Familial Heterozygous: High cholesterol is the presence of high levels of cholesterol in the blood. Familial means that is passed down through families and is a genetic disorder. The altered gene that causes familial high cholesterol is located on chromosome number 19.


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